ADHD: PEDIATRIC ANXIETY
Why do some young people who experiment with cannabis become daily users? Are their claims of medical use credible? Dr. O’Connell found that the vast majority of medical-marijuana applicants were already chronic users before they walked through the door of the dispensary. (People who try marijuana and have an unpleasant experience generally don’t go to physicians for letters of recommendation.) The everyday smokers he interviewed had remarkably similar medical and social histories. O’Connell determined that the main reason young people smoke cannabis on a regular basis is because it is a safe and effective way to relieve anxiety and other mood disorders associated with insecurity and low self-esteem.
Repetitive drug use usually entails a more serious purpose than mere recreation, according to O’Connell, who maintains that since the 1960s young Americans have embraced marijuana en masse to assuage the same emotional symptoms “that made anxiolytics, mood stabilizers and antidepressants Big Pharma’s most lucrative products.” “The need to self-medicate symptoms of adolescent angst is much more important than simple youthful hedonism,” O’Connell concluded.
For America’s youth, cannabis is like catnip for a cat, a poorly understood but nonetheless efficient herbal means of navigating the ambient anxiety and frenetic complexity of modern life. The emergence of marijuana as the anxiolytic drug of choice and its durable popularity among tense teens and anxious adults makes sense in light of scientific research that has documented the stress-buffering function of the endocannabinoid system.
Whereas activation of the body’s innate stress response (“fight or flight”) is essential for responding and adapting to acute survival threats, too much stress can damage an organism in the long run by depleting endocannabinoid tone. A compromised endocannabinoid system sets the stage for a myriad of disease symptoms and ups the risk of premature death. Chronically elevated stress levels boost anxiety and significantly hasten the progression of Alzheimer’s dementia. Emotional stress has been shown to accelerate the spread of cancer. Stress alters how we assimilate fats.
On a cellular level, stress is the body’s response to any change that creates a physiological demand on it. When a person is stressed, the brain generates cortisol and other steroid hormones, which, in turn, trigger the release of naturally occurring marijuana-like compounds: anandamide and 2-AG. These endogenous cannabinoids bind to primordial cell receptors that restore homeostasis by down-regulating the production of stress hormones. Marijuana, an herbal adaptogen, essentially does the same thing.
Martin A. Lee is the director of Project CBD and the author of Smoke Signals: A Social History of Marijuana — Medical, Recreational and Scientific.
Copyright, Project CBD. May not be reprinted without permission.